Phone: (215) 823-5804
Fax: (215) 222-5465
E-mail: rabano1@comcast.net

Position: Professor Appointed: 1970

Membership:

• American Society for Biological Chemistry
• American Chemical Society
• Society for Nuclear Medicine

Research:

I study lipid metabolism. Recent work indicates research on the turnover of phosopholipids of lung surfactant and factors involved in biosynthesis and the fate of the carbon skeleton of phosopholipids, mevalonate and steroids in different species of animals (crustaceae, mammals, etc.).

In addition we have examined the effects of ozone and hyperbaric conditions on lipid structure stability, tracing the pentration of labeled medications through the skin, gums, etc., and determining the intermediary metabolism of these drugs as well as the effects of lipids on their ability to be absorbed by the transdermal route. The carbon degradation of the skeleton of lipid structures and the significance of correct labeling of materials (alpha, omega, etc.) have helped interpret the significance of observed rate of biosynthesis and degradation of all lipids.

Publications:

1. J.L. RABINOWITZ, J.R. Gress, and J.E. Nixon, Lipid Composition of the Tissues of Human Knee Joints. II. Synovial fluid in trauma. Clinical Orthopedics and Related Research 190:293-298, 1984.
2. J.L. RABINOWITZ and D. Baker. Absorption of Labeled Triethanoline Salicylate in Human and Canine Knee Joints. II. J. Clinic Pharmacol. 24:532-539, 1984.
3. RABINOWITZ, J.L., Staeffen, J., Hall, C.L. and Brand, J.G. A Probable Defect in the beta-oxidation of Lipids in Rats Fed Alcohol for 6 Months. Alcohol, 8, 241-246, July 1991.
4. RABINOWITZ, J.L., Sheridan, O., Craig, R.G., Feldman, R., Grossman, E.R., Harvey, C.E. and Haskins, M.E.: Lipid Composition and Biosynthesis in the Gingiva of the Domestic Cat. J. Periodontology, 62, 495-498, August 1991.
5. RABINOWITZ, J.L., Baker, D.G., Villanueva, T.G., Asanza, A.P. and Capuzzi, D.M. Liver lipid profiles of adults taking therapeutic doses of aspirin. [Journal Article] Lipids. 27, 311-314, Apr 1992.
6. Huque, T., Brand, J.G. and RABINOWITZ, J.L. Metabolism of inositol-1,4,5-trisphosphate in the taste organ of the channel catfish, Ictalurus punctatus. Comparative Biochemistry & Physiology - B: Comparative Biochemistry. 102, 833-839, Aug 1992.
7. RABINOWITZ, J.L., Brand, J.G., Cowart, B.J. and Engen, R.L. Hepatic lipid profiles in miniature pigs after alcohol feeding. Alcohol, 11, 25-29, Jan-Feb 1994.
8. RABINOWITZ, J.L. and Myerson, R.M. Changes in the lipid content of rat lymph after the ingestion of [¹⁴C] long-chain fatty acids. Life Sciences. 54, 555-559, 1994.
9. RABINOWITZ, J.L. Salivary lipid profiles of the leech (Hirudo medicinalis). Lipids 8, 887-888, 1996.